PLATELET-RICH PLASMA (PRP), HYALURONIC ACID (HA) AND COMBINATION THERAPY FOR KNEE OSTEOARTHRITIS (KOA)

Knee osteoarthritis (KOA) is a prevalent degenerative joint disease that affects millions worldwide, leading to pain, stiffness, and functional limitations. While traditional treatments like nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroid injections have been commonly used, they often provide only temporary relief and may have side effects with long-term use. As leaders in Orthobiologics therapies, our PLYMOUTH MEDICAL team has seen them gain popularity as alternatives along our 14 year history. Some clinicians have also explored combining these treatments to enhance outcomes. This blog post delves into the efficacy of PRP, HA, and their combination in treating KOA, examining clinical evidence to determine the most effective approach.

The Patient's Guide to Optimal Orthobiologic Recovery Through Nutrition

Optimizing outcomes from Orthobiologic therapies relies on delivering the right nutrients to the body at the right time. These therapies depend on the body's natural ability to repair and regenerate tissue, which can be enhanced through strategic nutrient timing and targeted dietary support. This blog post outlines protocols for nutrient timing, dietary adjustments and supplement integration to promote optimal tissue regeneration during the post-Orthobiologic phase.

Summarizing the latest Meta-Analysis for PRP Dosing Across several Musculoskeletal Conditions

The systematic review & meta-analysis published in Current Review in Musculoskeletal Medicine in July 2024 compared outcomes across a range of platelet dosing and, once again, demonstrated that dose is the critical factor in the efficacy of PRP. The study goes into great detail, outlining specific dosing requirements based on the underlying pathology. Our latest blog post summarizes this groundbreaking study, led by Dr. William Berrigan of UCSF, a PLYMOUTH MEDICAL client, and organizes the findings by indication.

Understanding the Key Differences Between Radial Pressure Wave Therapy (EPAT) and Focused Shock Wave Therapy (ESWT)

This blog delves into the similarities and differences between radial and focused therapies. Understanding the nuances of these treatments will enable you to make an informed decision when recommending the most suitable approach for your patients' specific needs.

Unraveling the Complexities of Leukocytes in PRP: Macrophage Plasticity and its Implications for Tissue Repair and Regeneration

This blog post aims to better understand the different white cell populations that are often injected with platelets (PLTs) in everyday cell therapies and questions "old school" PRP nomenclature while diving deeper on macrophage plasticity and its effect on tissue repair and regeneration in Orthobiologics. 

Long-Lasting Benefits of High Volume Platelet-Rich Plasma Injections for Knee Osteoarthritis

PRP is a regenerative therapy that has been steadily gaining traction due to its potential for relieving pain and improving joint function in patients suffering from KOA. However, the adoption of PRP as a standard treatment has been hindered by the variations in the preparation and administration of the therapy in clinical settings. A recent study has shed new light on this issue, providing compelling real-world evidence of the effectiveness of standardized, high volume injections of very pure PRP in managing KOA.

Best Practices for Integrating Orthobiologics into your Clinical Practice

Integrating Orthobiologics into your practice can offer many clinically superior benefits to your patients and can also mitigate the diminishing returns most are experiencing from insurance-based procedures. The following are a handful of best practices that you can follow in order to ensure your team is leveraging these treatments effectively and safely. As the leading supplier of Orthobiologics devices and solutions, PLYMOUTH MEDICAL discusses the key considerations of integrating Orthobiologics into your practice in this blogpost. 

Consensus Achieved on Platelet Rich Plasma (PRP) Treatments for Musculoskeletal Pathology: A Comprehensive Analysis

Over the years, the medical community has seen a surge in the use of PRP treatments, especially in the fields of orthopedics and pain management. This form of treatment has particularly gained traction in addressing various musculoskeletal pathologies. Recently, a group of experts achieved a consensus on a majority of statements concerning PRP treatments for musculoskeletal pathology. Find out what experts agree on when it comes to PRP in MSK pathologies.

How Nitronox® Nitrous Analgesia Can Help Increase Patient Satisfaction

Help your patients relax and reduce anxiety while increasing procedure throughput. Nitronox® nitrous oxide analgesia can be an effective anxiolytic for a variety of medical and dental procedures. Nitronox® nitrous oxide analgesia is ideal for short, minimally invasive and non-invasive medical procedures where there is a need for pain management or minimal sedation.

Single vs Multiple Injections of Platelet-Rich Plasma (PRP) - What Works Best?

Is there a difference in effectiveness when comparing single vs multiple PRP injection protocols for knee OA? How many injections are needed before a therapeutic effect is observed?

Pain Management During Platelet-Rich Plasma Injections

Looking to reduce your patient’s discomfort during PRP injections? Learn what the research has to say about using local anesthetics in conjunction with PRP and how that may impact overall efficacy.

How to price PRP treatments?

The first question usually asked by a prospective patient considering PRP is, “How much will this cost me?” Make sure to consider your response as thoughtfully as you did when implementing a PRP program in your practice.

Which anticoagulant is best for PRP?

When choosing an anticoagulant for homebrew PRP formulations, consider the following: Platelet-Rich Plasma (PRP) is an autologous blood-derived product in which platelets are concentrated to at least five times whole blood concentrations to achieve therapeutic benefits.